Logical Biology 9 (1):22-41, 2009

HYPOTHESIS

http://im1.biz

 

© Truthfinding Cyberpress

CANCER FORMATION BY IPS

 

Cancer Cell Formation by iPS Techniques:

Mechanisms and Testing Approaches

 

Wei-Kang Zhang1*, Chun Zhang2, Jing Jean Zhang3, Shi V. Liu4*

 

1 Department of General Surgery, 2 Institute of Hematology, Union Hospital, Huazhong Science and Technology University, Wuhan, China

3 Waverly Primary Care, Cary, NC, USA

4 Eagle Institute of Molecular Medicine, Apex, NC USA

 

* Correspondence at SVL8EPA@gmail.com

 

(Received 2009-04-10; revised 2009-06-03; accepted 2009-06-08; published 2009-06-08*)

 

HIGHLIGHT

 

A hypothesis on how techniques used for inducing pluripotent stem (iPS) cells can transform normal cells into cancer cells is peer-reviewed and published here as an OA-OR (Open Access-Open Review) publication.

 

ABSTRACT

 

Published here is a hypothesis in its revised format after taking some comments of peer reviews into consideration.  However, some unreasonable criticisms by the peer reviewers were rebutted and these rebuttals are also published here along with the original version of this hypothesis.  Furthermore, rejections by the initial journal receiving this hypothesis and arguments against those rejections were published.  Finally, an open invitation for public comments on this publication is presented.

 

KEY WORDS

 

Cell, Stem Cell, iPS techniques, iPSCs, Cancer, Oncogenesis, Mitochondria, Energy metabolism, Metabolic mutation, Induction, Transformation, Peer review, Peer resistance, Transparency, Openness, Open Access, Open Review, OA-OR, Rejection, Revelation, Mainstream, Side stream, Revolution, Dogma

 

 

Quotation

 

“If scientists as a whole denounce an idea this should not necessarily be taken as proof that the said idea is absurd: rather, one should examine carefully the alleged grounds for such opinions and judge how well these stand up to detailed scrutiny.”

– Brian D. Josephson (1940-, Winner for the Nobel Prize in Physics 1973)

 

 

 

Notice

 

The full-length version of this publication can be obtained by email to  SVL8EPA@gmail.com with a SUBJECT line as “Request for Full-length publication on Cancer Formation by iPS Techniques”.