Top Watch  3(1):22-25, 2008

OPEN DISPLAT

http://im1.biz

 

© Truthfinding Cyberpress

IPS PUBLICATION

 

The Fast Track for Publishing iPS Research

 

Shi V. Liu

 

Eagle Institute of Molecular Medicine

 Apex, NC 27502 USA

SVL@logibio.com

 

(Received 2008-02-25; accepted 2008-05-01; published 2008-05-30*)

 

HIGHLIGHT

 

The speed of publishing research reports on iPS cells has created some world records that may be hard to beat.  But once the iPS “airplanes” go down people may ask why there was such hurry in release those flawed “airplanes” into the therapeutic cloning “sky”?

 

ABSTRACT

 

Within one and half years, at least 20 research reports have been published in various “top” journals.  Except for a relatively slow start, the speed of publishing iPS research reports was extremely fast.  Some papers were accepted within just two weeks of submission and put online in about three weeks.  Why would “top” journals rush in publishing iPS research paper?  Did they give these papers the much needed scrutiny?  Why all these “top” journals would keep a tight suppression on criticisms on their publications on iPS cells?

 

KEY WORDS

 

Stem cell, ES, iPS, Cloning, Induction, Reprogramming, Regeneration, Hype, Spinning, Fast track, Publish

 

 

Since the publication of the first iPS research paper in 2006 [1], at least 20 research papers on iPS cells have been published so far (Table 1).

 

Although there was a little “hesitance” in publishing the first research report on iPS cells [1], once the barrier was broken, the speed of publishing iPS research has become faster and faster, especially for some selected research groups.

 

For examples, Yamanaka’s second iPS paper submitted to Cell was accepted in 13 days and published in 22 days.  A few other iPS researchers seemed also to have the capability of running the fast tracks in publishing.

 

However, coming with this rush was also some relaxing of scrutiny.  As a matter of fact, these “top” journals even did not care about doing a descent job because some very obvious mistakes happened in the “high quality” journals [2-4].  More amazingly, the fast publication of iPS research reports was made while these journals suppressed the publication of some strong criticisms (http://im1.biz/Cloning.htm).

 

Thus, once the hyping and misrepresentation is realized by the mainstream, it would be a great shame that those “experts” could not detect some obvious flaws in the iPS research.  It would also be a great irony that the “top” journals were at the bottom of publishing truth.

 

 

Table 1. A chronological list of experimental research reports on iPS cells

 

No

Reference

Group

Received

Revised

Accepted

Publish online

Publish in print

Accepted

 

Published **

1

Takahashi 2006 [1]

1

2006-04-24

2006-06-18

2006-06-20

2006-08-10

Cell 126:663, 2006

<2m

~4m

2

Okita et al 2007 [5]

1

2007-02-06

 

2007-05-22

2007-06-06

Nature 448:313, 2007

~3m

~4m

3

Wernig et al 2007 [6]

2

2007-02-27

 

2007-05-22

2007-06-06

Nature 448:318, 2007

<3m

~4m

4

Maherali et al 2007 [7]

3

2007-03-31

2007-05-04

2007-05-14

2007-06-06

Cell Stem Cell 1: 50, 2007

<2m

~2m

5

Blelloch et al 2007 [8]

4

NR

NR

NR

NR

Cell Stem Cell 1: 245, 2007

NA

NA

6

Mann et al [9]

9

NR

NR

NR

NR

Nature Method August 2007 page i

NA

NA

7

Meissner et al [10]

2

2007-05-29

 

2007-08-09

2007-08-27

Nature Biotechnol. 25:1177, 2007

<3m

~3m

8

Qin et al.